How to drink Glucophage Long 750 for weight loss. Glucophage for weight loss: instructions for use and analogues. When is an appointment necessary?

It so happened that the drug, intended strictly for the treatment of diabetes, has become very popular among those losing weight. Endocrinologists constantly warn that Glucophage should not be used for weight loss, that it is a very serious medicine that can cause deadly side effects, including coma.

But when you can’t, but really want to, no prohibitions will stop those who want to lose weight. Therefore, we will tell you how to properly lose weight with Glucophage, and what precautions you need to take.

How Glucophage works for weight loss

Glucophage can truly be called the dream of all those losing weight. It consists of the active substance metformin, which prevents eaten carbohydrates from being absorbed from the intestines into the blood. As a result, carbohydrates leave the body in stools that are looser than usual, more frequent, and with an abundance of gas. If you overindulge in sweets, you may experience stomach pain.

Since glucose does not enter the blood, it means that the hormone insulin, which is responsible for its conversion into fat reserves, will not be produced. problem areas our body. But that's not all. After all, the body constantly needs energy to live, but its most easily digestible source – carbohydrates – is not available. And then the accumulated fats begin to burn. And if you also follow a low-calorie diet, then weight loss on Glucophage goes even faster.

And one more feature of Glucophage: it reduces appetite. In this case, there may be nausea and a metallic taste in the mouth, but even these side effects do not stop those losing weight.

How to take Glucophage for weight loss

If the person losing weight does not have diabetes (otherwise an endocrinologist would prescribe the medicine and dosage), it is enough to drink a Glucophage tablet with a minimum dose: 500 mg 2-3 times a day during main meals or immediately after meals. The tablet must be swallowed without chewing and washed down with at least half a glass of water. You can take Glucophage for no longer than 3 months, and repeating the course is allowed only after a 3-month break.

In order not to get dangerous complications from taking Glucophage, you need to remember:

You can’t fast (the daily calorie content of food should be at least 1000 kcal);

You cannot work hard physically or carry out exhausting sports training(a deadly complication may occur - lactic acidosis);

Do not take diuretics, as well as medications and vitamins containing iodine at the same time as Glucophage;

It is necessary to discontinue the drug during acute intestinal or cold infections accompanied by diarrhea or fever.

Finally, a small fly in the ointment for the lazy: you shouldn’t hope that you will be able to lose weight with Glucophage without doing sports or at least exercising. The body, without receiving glucose from food, still synthesizes it, and Glucophage will drive it into the muscles. If it is not burned there during exercise, it will turn into fat.

And remember, taking Glucophage to lose weight is an extreme that doctors do not approve of. Weight loss can be achieved by eliminating starchy, sweet and fatty foods, switching to diet foods, eating a lot of protein foods and moving. If you want to help your body lose weight, it is better to take natural dietary supplements for weight loss.

Sometimes problems with overweight lies in problems related to blood. In this case, a person can eat right and exercise, but the excess weight will not go away. This is due to the high level of insulin in the blood. Solving this problem requires a specialized approach. The drug Glucophage will help cope with this.

Glucophage is a drug created for the treatment of diabetes mellitus. Active substance. With its help, you can normalize insulin levels in the blood and get rid of excess weight.

Impact on the body:

1. After taking the tablets, the concentration of glucose in the blood decreases.
2. The intestines stop absorbing large amounts of glucose.
3. The main organs, tissues and cells of the body become sensitive to insulin.
4. Glucophage long for weight loss slows down the process of absorption of carbohydrates by the digestive tract.
5. Insulin synthesis remains normal.
6. Prevents blood sugar from dropping below normal levels.
7. Dulls the feeling of hunger.

However, in order to improve the functioning of this drug and not dampen its effect on the body, it is necessary to combine it with special nutritional methods. They should not contain fast carbohydrates.

Release form

The drug is produced in packages containing from 30 to 100 pieces to choose from. At the same time, you can find Glucophage 500 for weight loss, 750, 850, 1000 and long for weight loss. They differ in their effect on the body and the amount of active substance in milligrams.

Compound

Glucophage contains not only metformin. It also includes other components:

• magnesium sterate;
• microcrystalline cellulose;
• shell made of hypromellose;
• povidone.

You can purchase tablets only with a doctor's prescription. Country of origin: France.

Contraindications

Like any other medicine, glucophage has certain contraindications. It is not prescribed in the following situations:

1. Individual intolerance to the active substance or components. The appearance of allergic reactions.
2. Problems related to kidney function.
3. Pregnancy and.
4. Liver dysfunction.
5. Mental and infectious diseases.
6. Exacerbation of chronic diseases.
7. Simultaneous low calorie diet.
8. Postoperative period.
9. Diseases of the cardiovascular system.
10. Long-term bowel dysfunction.

Before using the drug, be sure to consult with your doctor. A specialist will select a safe dosage and protect you from possible side effects.

Side effects

Many people wonder why you can’t eat sweets with glucophage? Any products containing sugar can destroy the effectiveness of the drug and work in the opposite direction. The same goes for fast carbohydrates. Also, we must not forget about possible side effects. These include a metallic taste in the mouth, stool problems, and frequent pain in the stomach and intestines. Sometimes skin rashes, redness and itching appear.

Mostly, side effects can occur in the first days of using the drug and in cases where you take it long before meals. If any of the side effects bother you for several days, stop taking the drug and consult your doctor.

Analogues of Glucophage

This drug has many analogues that can be easily found in any pharmacy:

1. Metformin hydrochloride.
2. Formetin.
3. Sophamet.
4. Glycon.
5. Metaspanin.
6. Langerin.
7. Metformin.
8. Metadiene.
9. Glucophage Long.
10. Metfogamma 850.
11. Novoformin.
12. Metfogamma 1000.
13. Combogliz.
14. Bagomet.
15. Metfogamma 500.

You can purchase the drug and its analogues in the price range from 100 to 600 rubles. It all depends on the number of capsules in the package and the country of manufacture.

Weight loss

The drug primarily affects, actively reducing it. However, it has an additional effect on weight loss. Glucophage dulls hunger, so a person begins to eat less and, accordingly, lose weight. Also, a large amount of insulin contributes to the accumulation of fat in the abdominal area. Reducing it will lead to the disappearance of fat in the problem area.

Application and dosage

An important question for a patient who is interested in this drug is how to take glucophage for weight loss? Tablets can only be taken orally. There are no other variations of Glucophage. Doctors recommend purchasing tablets containing 500 mg of the active substance for weight loss. To avoid side effects associated with digestion, you need to take three tablets per day during main meals.

The duration of the course is 20 days. If the result is not enough, you need to take a break and only then repeat the treatment. The doctor prescribes glucophage for weight loss according to the instructions or creates an individual course depending on the characteristics of the patient’s body.

In order for the weight loss process to take place with the greatest effect, doctors give the following recommendations:

1. Do not increase the dosage of the active substance. This will not lead to an increase in the effect, but on the contrary, it can cause many side effects.
2. Increase quantity. Start playing sports. Spend more time outdoors.
3. Completely give up bad habits.
4. Stick with it. Portions should be small.

Use after childbirth

Whether to use Glucophage after childbirth or not is a controversial issue among experts. During the period of bearing a child, girls in most cases gain overweight. This may be due to changes in the body hormonal imbalances, small physical activity and other reasons. There is no consensus on whether diabetes medication should be used solely for weight loss.

Experts' opinion

Ekaterina Semenikhina, 40 years old (Novosibirsk), nutritionist, 12 years of experience:

I am familiar with the problems of people with high insulin levels in the blood. Yes, without additional help and eliminating this violation makes it difficult for them to lose extra pounds. When such a person turns to me for help, I prescribe Glucophage or one of its analogues. At the same time, a technique is selected proper nutrition and I call on a person to healthy image life. An integrated approach to solving this problem shows good results.

Sergey Nikitin, 42 years old (Moscow), nutritionist, 14 years of experience:

Familiar with drugs that lower insulin levels in the blood. As for Glucophage, I do not prescribe it simply for weight loss. I don’t see the point in stuffing the body with pills if the problem can be dealt with using a properly designed weight loss technique and additional physical exercise. However, in some situations it is simply irreplaceable.

Conclusion

Based on the opinion of experts, the effect on the body and additional properties, Glucophage is an excellent remedy for people with high insulin levels. In such situations, it is important to choose the right diet, diversify your day with sports and street walks. If you follow the rules, you can improve your body's condition and lose weight.

The site provides background information for informational purposes only. Diagnosis and treatment of diseases must be carried out under the supervision of a specialist. All drugs have contraindications. Consultation with a specialist is required!

General information

Composition and dosage forms: 500, 850 and 1000

Long

Mechanism of action

The mechanism of action of glucophage is based on the fact that it increases the sensitivity of receptors to insulin and accelerates the processing of sugars by muscle cells. Reduces the deposition of glucose in the liver, as well as the absorption of carbohydrates by the digestive organs. It has a good effect on fat metabolism: it reduces the amount of cholesterol, triglycerides and low-density lipoproteins.

The bioavailability of the drug is at least 50%. It is very quickly absorbed through the walls of the gastrointestinal tract and the maximum amount of the drug in the blood is determined two and a half hours after oral administration.

The active substance does not interact with blood proteins and spreads very quickly throughout the cells of the body. It is practically not processed by the liver and is evacuated from the body with urine.
There is a possibility of inhibition of the drug in tissues in individuals with reduced renal function.

When is an appointment necessary?

• Type 2 diabetes mellitus in persons over 18 years of age,
• in combination with insulin therapy for type 2 diabetes mellitus, in particular with severe obesity and the body’s immunity to insulin,
• type 2 diabetes mellitus in adolescents and children over 10 years of age, both as a single therapeutic drug and in combination with insulin.

Contraindications

• Ketoacidosis in diabetes,
• precoma in diabetes,
• coma due to diabetes
• renal failure, creatinine clearance less than 60 mlmin,
• acute conditions that impair kidney function: dehydration due to diarrhea or vomiting, severe infections, lack of oxygen in tissues, fever,
• any disease that causes a lack of oxygen in the tissues ( pulmonary and heart failure, acute myocardial infarction),
• injuries and operations,
• severe liver diseases,
• alcohol intoxication and chronic alcoholism,
• lactic acidosis ( including transferred),
• two days before and two days after the X-ray using contrast with iodine compounds,
• diet containing less than 1000 kilocalories per day,
• During pregnancy and breastfeeding ,
• individual intolerance to components.

Dosage and regimen for diabetes

For adult patients, the initial dosage is 500 mg of the drug two or three times a day with food or immediately after. Taking into account individual indicators of the amount of glucose in the blood, you can subsequently increase the dosage.

To stabilize glucose levels, you should take from 1500 to 2000 mg per day. To reduce the likelihood side effects of the drug you need to take glucophage two or three times a day, but not more than 3000 mg per day in three days.

A gradual increase in dosage will lead to the adaptation of the gastrointestinal tract and a decrease in the intensity of side effects.

With a daily dosage of 2000 to 3000 mg, it is more advisable to take a drug containing 1000 mg of the active ingredient in one tablet. The daily dosage should not exceed 3000 mg received in three days.

If, before taking Glucophage, the patient had previously used another drug to lower blood glucose levels, it should be completely discontinued and taken in the same quantities as recommended above.

In combination with insulin
For getting highest result To maintain the amount of glucose in the blood, glucophage should be combined with insulin.

Primary doses are 500 mg or 850 mg twice or thrice daily or 1000 mg once daily. The amount of insulin should be taken depending on the level of glucose in the blood.

Adolescents and children over ten years of age can be given either glucophage in combination with insulin or as the only drug. In the first days of treatment, you should take 500 mg of the drug two or three times a day with or after meals. After one and a half to two weeks, the amount can be changed depending on the glucometer readings. Children can be given no more than 2000 mg of the drug per day in two or three doses.

Elderly people suffering from impaired renal function should select the amount of the drug individually based on glucose and creatinine levels. The level of creatinine in the blood is measured every 3 to 6 months.

Dosage of glucophage long
The tablets should not be crushed or chewed and should only be swallowed whole.
The primary dosage of Glucophage Long is one 500 mg tablet ( or 750 mg) once a day in the evening during meals.

Further, the dosage is adjusted depending on the blood sugar level.
You can increase the dose once every two weeks depending on the blood sugar level; this is done gradually, bringing it to the maximum daily amount.

The maximum allowed dosage is 2 grams ( 2.25 when taking 750 mg tablets) per day, which should be taken once a day in the evening with meals.
Sometimes taking the drug twice a day is more effective.

You should not interrupt taking the drug; if one tablet is accidentally missed, the next one should be taken at the usual time. Do not exceed recommended dosages.

For those persons who take the drug in regular form in quantities of more than 2 grams per day, they should not be changed to the Long form.
The Long form is not prescribed to persons under 18 years of age, since there is no data on clinical trials of this drug in this group of patients.

Side effects

Allergic manifestations: urticaria.

Overdose

What to do?
Stop taking the drug immediately and call an ambulance. In the hospital, the amount of lactate in the victim’s blood is measured and his condition is alleviated with medications. Hemodialysis is used to cleanse the body of metformin and lactate.

Glucophage and alcohol

During pregnancy and breastfeeding

There is no reliable information about the penetration of the drug into breast milk. However, it should not be taken while breastfeeding.

Combination with drugs

• danazol,
• ethanol-containing products,
• chlorpromazine in dosages of 100 mg per day and above,
• neuroleptics,
• loop diuretics,
• iodinated contrast agents for x-rays,
• beta2-sympathomimetics.

Use for weight loss in obesity

In addition, insulin provokes a feeling of hunger, and the use of metformin helps to ensure that hunger occurs as rarely as possible.

The effectiveness of this drug decreases with increasing acidity of the internal environment of the body. Therefore, in some sources you can find advice not to engage in active physical activity while taking this drug. After all, playing sports increases the level of lactic acid. But most researchers believe that physical exercise have no effect on the overall acidity of the blood. That is, you can afford your favorite trips to the gym or jogging in the park.

Glucophage is not harmful to health if taken as prescribed. It can be used to reduce body weight. But to get results you must combine the drug with special diet, which does not contain fast carbohydrates.

To lose weight you need:

• give up fast carbohydrates,
• adhere to dietary nutrition,
• take glucophage in the amount of 500 mg before meals 3 times a day,
• if diarrhea appears while taking the drug, it is likely that your diet contains a lot of carbohydrate foods,
• if nausea occurs while taking the drug, the amount should be reduced by half,
• for getting best result You should do aerobic exercise from time to time.

Diet upon admission

So, you need to completely avoid the following products:

• sugar and food in which it is present,
• grapes, figs and bananas,
• dried fruits,
• juices with sugar,
• potatoes, especially in the form of mashed potatoes.

For polycystic disease and infertility

At the Federal Endocrinological Center under the Ministry of Health Russian Federation A group of scientists conducted research on the effectiveness of glucophage in polycystic ovary syndrome against the background of metabolic syndrome. 70 patients took part in the experiment, average age which is 25 years. They took 1500 mg of the drug per day for six months. The first three weeks the dosage was minimal, gradually it was increased to the specified one.

In addition to taking the drug, all patients followed a diet. According to the results of the experiment, all participants normalized the body's sensitivity to insulin, decreased body weight, and normalized cholesterol and triglyceride levels in the blood.

Glucophage for weight loss: how to take it correctly
I started gaining weight after I turned 30. For a long time I couldn’t understand what was going on. I tried many diets and tried to play sports. The first did not help, the second did not have enough willpower. Recently I was admitted to the hospital with a common cold.

They gave me a referral for a blood test. It turned out that my sugar level was higher than normal. After talking with an endocrinologist, I learned that drugs such as Glucophage, if taken correctly, are ideal for weight loss.

I didn’t take any risks; I did everything according to the specialist’s instructions. The result appeared after about 2 months. So far, the weight continues to decrease slowly but steadily.

Glucophage, what kind of drug is this?

Glucophage is a drug intended to maintain the well-being of people with diabetes. It contains substances that reduce blood sugar and insulin levels, which leads to the burning of subcutaneous fat deposits. It is because of this property that this drug began to be used for weight loss.

Unlike other drugs that have the ability to burn fat cells, glucophage has very few side effects, and they only occur when the drug is taken incorrectly. The main goal of glucophage is to reduce the level of bad cholesterol and blood glucose, which are often elevated in obese people.

This drug also has the following abilities:

• reduce the absorption of carbohydrates, which are the cause of excess weight;
• oxidize for a short time fatty acid, which enter the body when eating;
• activate AMP kinase, which causes fat cells to be destroyed;
• suppress glucose synthesis in the liver;
• improve the process of delivering glucose to the muscles, thereby increasing their nutrition, which is very important when losing weight;
• increase the level of sensitivity to insulin receptors.

Scientists have proven more than once that as soon as food enters the body, the level of glucose in the blood begins to increase sharply, as a result of which the pancreas begins to work, producing large amounts of insulin.

It is the appearance of a large amount of insulin in the body that leads to the fact that glucose begins to be deposited in tissues and form fat cells.

It is for this reason that nutritionists do not recommend eating foods high in sugar, which can cause a strong increase in blood glucose levels. Taking glucophage leads to a dulling of hunger and a decrease in appetite, which is caused by insulin. Taking Glucophage allows you to normalize all processes of metabolism and absorption of nutrients.

This drug reduces and controls the production of glucose and insulin, which means only one thing: fat deposits will stop being deposited and you will stop gaining weight.

And since the body will have nowhere to get energy from, it will begin to burn its own reserves, dissolving fat cells located in such problem areas of the body as the thighs and abdomen.

Taking glucophage for the purpose of weight loss is approved by doctors, and this is its peculiarity. However, they still advise observing at least some dietary restrictions during this period. This is especially true for easily digestible carbohydrates, which are found in chocolate, buns and other goodies. If you allow yourself to eat even one bun, then you will reduce the entire effect of the drug to zero and the process of glucose deposition will resume.

Source: evehealth.ru

How does glucophage affect the body during weight loss?

Glucophage can truly be called the dream of all those losing weight. It consists of the active substance metformin, which prevents eaten carbohydrates from being absorbed from the intestines into the blood. As a result, carbohydrates leave the body in stools that are looser than usual, more frequent, and with an abundance of gas. If you overindulge in sweets, you may experience stomach pain.

If you follow a low-calorie diet, then losing weight on Glucophage goes even faster.

If glucose does not enter the blood, it means that the hormone insulin, which is responsible for its conversion into fat reserves in problem areas of our body, will not be produced. But that's not all. After all, the body constantly needs energy to live, but its most easily digestible source – carbohydrates – is not available. And then the accumulated fats begin to burn.

And one more feature of Glucophage: it reduces appetite. In this case, there may be nausea and a metallic taste in the mouth, but even these side effects do not stop those losing weight.

Source: dietplan.ru

Useful properties of Metformin

Today, new properties of metformin are being discovered and its use is expanding quite significantly, using the drug not only in complex therapy for diabetes mellitus.

The drug Metformin has long been used to treat type 2 diabetes mellitus in conjunction with diet therapy prescribed by a doctor. It allows not only to normalize blood glucose levels, but also helps to reduce excess weight, which is especially important for people with this diagnosis.

To date, other features of the drug have also been identified. It has been scientifically established that a person can take Metformin to achieve the following goals:

1. Helps protect the brain from aging, which allows it to be used for preventive purposes against Alzheimer's disease.
2. Has a beneficial effect on the condition of blood vessels and arteries. Thus, with the help of Metformin, the development of vascular atherosclerosis, heart failure, hypertension, and vascular calcification can be prevented.
3. Reduces the likelihood of cancer.
4. Actively affects the improvement of potency in men, which was impaired as a result of various senile diseases.
5. Neutralizes the development of osteoporosis in diabetics. Women especially often suffer from brittle bones after menopause, as there is a significant decrease in hormones - estrogens.
6. Has a beneficial effect on performance thyroid gland.
7. Shows a protective function in relation to the respiratory organs.

Even though the drug has so many benefits, it cannot be said that it is healthy and can cure many diseases. Like other medications, Metformin can be used only as prescribed by the attending physician, taking into account the possibility of all its side effects and contraindications.

Source: diabetes.guru

Glucophage for weight loss - how to take it correctly? Types of the drug

The tablets are packaged in 30 and 60 pieces, in the form of oblong capsules. It is better to take the drug for weight loss, starting with small doses, gradually increasing to the required ones.

You need to start losing weight correctly with a dosage of 500-1000 per day; if the body reacts normally, you follow this initial regimen for several days, and then gradually increase its intake to the required norm.

Typically, Glucophage for weight loss is adjusted to a consumption of 1500 - 2000 mg per day, but not more than 3000 mg. The instructions recommend taking the tablets during meals or immediately after. A certain daily dose should be divided evenly into 3 doses - for breakfast, lunch and dinner. You need to wash it down with a small amount of pure mineral water.

It is very comfortable to take tablets at a dosage of 500 mg; here you just need to take them 3 times a day, without making any calculations or divisions. Dosages of 850 and 1000 will be needed if you decide to take a more serious dosage - up to 3000 mg of the drug per day.

You need to carefully monitor your condition; if you feel discomfort or nausea, you need to reduce the dose by half and stay at this dosage for several days. When the condition returns to normal, gradually increase the dosage. If diarrhea occurs, one of the associated side effects of Glucophage, the first thing to do is to reduce the amount of carbohydrates you eat.

Glucophage Long tablets for weight loss are characterized by a prolonged action, with a gradually releasing active ingredient.

The peculiarity is explained by the special property of the active components, which require more time to be absorbed. Ultimately, the absorption of Glucophage Long will continue throughout the day, and its use for weight loss is required in smaller quantities than standard tablets of 500, 850, or 1000 mg. It only needs to be taken once or twice a day, although the dosage is 500 and 750 mg.

But the advantage of such a prolonged action is the virtual absence of side effects, since there is a gradual release of the active component and, accordingly, the body gradually gets used to it.

Physical activity must be present, but light, aerobic. Intense workouts leave it for later, otherwise it can cause harm to your health.

More important feature Using Glucophage for weight loss will require you to adhere to a diet. Nutrition should be balanced, but for effective weight loss, provide the body with a daily calorie deficit.

It is unacceptable to consume refined foods containing fast carbohydrates. You need to eat fiber, fresh vegetables, protein, beans. But potatoes, sweets, flour, grapes and bananas should be excluded from your diet at least for the duration of the diet.

Source: bezpuza.ru

Glucophage Long

Glucophage Long is one of the varieties of the drug Gluconage. It has a longer action, since, unlike tablets, it has long-term absorption. This product is available in two forms: 500 mg and 850 mg. Glucophage Long should be taken with meals in the morning and evening.

My mother takes Glucophage Long as prescribed by an endocrinologist. She had high blood sugar (12). But she was also very worried about the problem of excess weight. After all, she weighed more than 100 kg with a height of 156. With the help of this drug, it was possible to reduce sugar to 7 units. Mom also lost 12 kg, and I think this is an excellent result.

Within a couple of hours, the level of active components in the blood will reach its level, which will help reduce appetite during lunchtime and at night. The peculiarity of this drug is also that it does not affect the liver. Its components are excreted from the body naturally through urine.

The price for this type of drug varies from 300 rubles. up to 750 rub. depending on the mass of the active substance.

Source: evehealth.ru

Glucophage 1000

This is another type of the drug Glucophage, which is distinguished by its large dosage. It is used in different ways. For some, two tablets a day are enough to start the fat burning mechanism, while others need three.

Reviews of the drug Glucophage Long:

Elizaveta Pristina

My mother (56 years old) weighs 125 kg with a height of 165 cm. She is diagnosed with diabetes and obesity. Takes glucophage 1000 mg 2 times a day. I follow a diet and do cardio training 2 times a week. Sugar levels are now almost normal. The weight also went down (now 118).

Glucophage 1000 is taken in the same way as other types of this drug: one tablet before or during meals. Drink plenty of water. Remember, for this drug to bring positive results, you should avoid eating various sweets, flour and all other foods that contain easily digestible carbohydrates.

The price for this type of drug varies from 200 rubles. per pack of 30 tablets.

Source: evehealth.ru

Dietary nutrition when taking glucophage for weight loss

A diet when taking Glucophage is required. Moreover, you will have to adhere to it even after completing the treatment course. The only consolation for those who like to snack from the heart is milder conditions than during fasting or express diets.

You can choose either a balanced or unbalanced menu. In the first case, the body will steadily receive all the necessary nutrients from food, while the number of calories consumed will be reduced. The second option focuses on dishes high in carbohydrates, but completely excludes lipids from the diet.

In both cases, your menu should include foods high in plant fiber (beans, grains, peas). But you will have to forget about sugar and sugar-containing products completely.

Glucophage is a potent drug and has a fairly extensive list of contraindications and side effects. Therefore, healthy people (who have no other indications other than being overweight) should not drink it as a means of losing weight. The achieved result will be short-lived, but the health consequences will be severe.

Source: hudeyko.ru

Contraindications for use

The drug should not be used if the patient has the following physiological or pathological conditions:

• Individual hypersensitivity to the active or any of the auxiliary components of the drug.
• Age less than 18 years. This ban is due to the lack of sufficient information to judge the safety of the drug when used in patients of this category.
• Pregnancy.
• Following a low-calorie (up to 1000 kcal/day) diet.
• Use within two days before or after X-ray or radioisotope studies involving the administration of an iodine-based contrast agent.
• History or diagnosis of lactic acidosis.
• Alcoholism in the chronic stage.
• Alcohol poisoning in acute form.
• Liver dysfunction.
• Failure of kidney function.
• Presence of injuries or surgical interventions involving insulin therapy.
• Pronounced manifestations of diseases in chronic and acute forms that can provoke tissue hypoxia. Such diseases include myocardial infarction (acute form), respiratory failure, chronic heart failure, characterized by unstable hemodynamic parameters, acute heart failure.
• Diseases that occur in an acute form and can provoke impaired renal function and dehydration (repeated bouts of vomiting, severe or chronic diarrhea), as well as severe diseases of infectious etymology and shock conditions.
• Impaired renal function, insufficient renal function.
• Diabetic ketoacidosis, coma, diabetic precoma.

Source: nastroy.net

Drug interactions

The correct dosage is far from the only indicator that affects the effectiveness of Glucophage. If you combine it with another drug, the result can often be unpredictable.

Prohibited combinations:

1. Parallel use with alcohol and alcohol-containing drugs in the vast majority of cases ends in failure. The patient first develops hypoglycemia, then falls into a hypoglycemic coma and (in the absence of emergency help) dies.
2. If you do not limit yourself to consuming foods high in glucose (for example, white sugar or sweets) while taking the drug, then your attempts to lose weight will be like fighting windmills.
3. Iodine-containing radiocontrast agents are also absolutely incompatible with Glucophage. Therefore, if you do not want to develop lactic acidosis, you should stop taking the drug 2 days before radiological and x-ray examinations. The course should also be resumed no earlier than after 48 hours (provided that during the examination no deviations in the work were identified internal organs).
4. Eating on express diets in combination with taking this drug threatens to result in serious interruptions in the functioning of internal organs. During the course of treatment (weight loss), the body must receive all the necessary minerals and vitamins.

Combinations requiring increased caution:

• If you plan to combine this drug with diuretics and drugs with indirect hyperglycemic action, be prepared to check your blood glucose levels more carefully and frequently.
• The combination of Glucophage + loop diuretics against the background of renal or functional liver failure threatens to result in lactic acidosis.
• When trying to combine it with insulin, salicylates and sulfonylurea derivatives, the patient's disease with hypoglycemia has been identified more than once.
• Cationic and antihypertensive drugs can contribute to significant adjustments in the dose of the drug and the course of its use.
• Nifedipine, chlorpromazine and a number of beta2-adrenergic agonists increase the concentration of glucose in the blood, and therefore, at high dosages, can neutralize the effect of the drug aimed at reducing it and provoke the prescription of insulin.
• You should not take Reduxin and Glucophage together without first consulting your doctor. Although these drugs have a similar principle of action, the result of combining them can be a double whammy internal systems body.

The drug market is developing more and more dynamically every year. Therefore, if you do not find other medications you are taking in these lists, this does not mean that their use in conjunction with Glucophage will not have negative consequences.

You can also protect your body from unnecessary risks only by consulting a doctor. This way you won’t confuse the dosage, and you will learn about the nuances of complex administration known only to an experienced specialist.

The tablets contain the active substance - metformin hydrochloride 500, 850, 1000 mg.

Additional components: povidone and magnesium stearate.

The film shell consists of hypromellose, and the 1000 mg tablets also contain Opadry Klia, Macrogol 400 and 8000.

Release form

The medicine is available in white film-coated tablets. Moreover, tablets of 500 and 850 mg are round in shape, and 1000 mg are oval. The drug is offered in 20 pcs. per cell, 3 cells per pack.

pharmachologic effect

The tablets have hypoglycemic effect.

Pharmacodynamics and pharmacokinetics

This drug can reduce hyperglycemia without causing development hypoglycemia . This does not stimulate secretion insulin , the hypoglycemic effect does not appear in healthy people.

There was an increase in the sensitivity of peripheral receptors in relation to insulin and recycling glucose cells. The production of glucose by the liver is reduced by inhibiting glycogenolysis and gluconeogenesis. The drug inhibits the absorption of glucose in the gastrointestinal tract.

β2-adrenergic receptor stimulants can increase blood glucose levels. In this case, glycemic control is necessary, and insulin may be prescribed. Combination of Glucophage and derivatives sulfonylureas, insulin, acarbose, salicylates enhance the hypoglycemic effect.

Terms of sale

The medicine is released strictly according to prescription.

Storage conditions

The tablets should be stored in a dark, cool place, out of reach of children.

Best before date

The shelf life of Glucophage 500 and 850 mg is 5 years, Glucophage 1000 mg can be stored for 3 years.

Analogs

The main analogues are represented by the following drugs: Bagomet, Glycon, Gliminfor, Langerin, Metospanin, Metadiene, Siafor and others.

Glucophage and alcohol

It has been established that alcohol can cause the development of lactic acidosis in acute alcoholism. The situation can be aggravated by liver failure, fasting, or following a low-calorie diet. Therefore, during this period it is necessary to refrain from combinations with ethanol.

Glucophage for weight loss

It should be noted that this drug is very popular among people who are losing weight. However, reviews from doctors report that this method of combating excess weight is very dangerous and can cause serious complications. However, this particular method is discussed on various forums where users are interested in how to take Glucophage for weight loss?

At the same time, some people recommend taking Glucophage 500 mg, explaining that such a dosage will be enough to “start metabolic processes" Others, on the contrary, advise Glucophage 850 mg, since a higher dosage “will only speed up the process.”

It is interesting that reviews for losing weight with this drug do not describe specific results. But at the same time, there are reports of a deterioration in general health, the development of abdominal pain, nausea and even vomiting. Therefore, experts advise starting to monitor your diet, which should be nutritious. It is necessary to exclude sweets, flour and fatty foods from the diet and increase physical activity.

Reviews of Glucophage

In most cases, discussions of this drug are related to its use for weight loss. At the same time, some reviews of those losing weight about Glucophage report that their doctor recommended this method to them, since diets and physical activity did not help eliminate excess weight. Other users are interested in how to take this medicine to quickly lose extra pounds. In addition, you can find stories from patients who took these pills to restore reproductive function.

However, using the drug for such purposes is not always effective. Moreover, both reviews from doctors and patients contain information about the development of serious pathologies against the background of such experiments.

Reviews of Glucophage for weight loss also do not describe specific results. Although patients who take the medicine for, note its effectiveness and gradual loss of body weight.

Glucophage price, where to buy

The price of Glucophage 1000 mg varies between 300-350 rubles.

The price of Glucophage 850 mg is from 205 rubles.

You can buy 500 mg tablets for 170-200 rubles.

The medicine Glucophage, intended specifically for weight loss, is not available.

• Online pharmacies in Russia Russia
• Online pharmacies in Ukraine Ukraine
• Online pharmacies in Kazakhstan Kazakhstan

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